Yen Lo approached human behavior in terms of fundamental components instead of metaphysical labels. His meaningful goal was to implant in the subject’s mind the predominant motive, which was that of submitting to the operator’s commands; to construct behavior which would at all times strive to put the operator’s exact intentions into execution as if the subject were playing a game or acting a part; and to cause a redirection of his movements by remote control through second parties, or third or fiftieth parties, twelve thousand miles removed from the original commands if necessary. The first thing a human being is loyal to, Yen Lo observed, is his own conditioned nervous system.

–The Manchurian Candidate by Richard Condon